SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e15164cb4032ca14920626e78db6d8bcb6355977bea7a90d55c8b141d691e7a' 
  AND token = 'OAlcEYD5TzIpLXT1TOSWg1mBWB/lk/aI+5uP4YkWQdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}