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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ef26f7e3e3af5213668bd1c50cd3de91eecb9e373954b1bd86017ed910a3ba' 
  AND token = 'N+m8S6OZM27Z4Z+zNdexGNYUQK34KAxo26gQ427NwZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}