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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c0f67802fa1f74796f1e652ebb413f296b0ea90e493786ecc61b34f923716e' 
  AND token = 'XlqOyMXTTj+nkJD5kRct7ihnMJQOVw0jsMl9QSAkfDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}