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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec1f2063acb2d213880d1611da871c50f72c92538fa216a2e06c79017ed931e1' 
  AND token = 'Zr2jfg8c77KvS8GUI6I4htcAB36b1Tr6mH8wQ8V+JoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}