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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '785c874e1a37b4e4ab7de7d47ca71820f2f2f2926141c5fa2d1b77d4c35328bb' 
  AND token = 'noJSeYTFiEprLs8xq0Qz0JgxDklc+y8hZvGel6Z24ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}