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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd590a4141d7cefc919dd052edf8598515ab5538450e35e8d19a16e7c00ed8b7a' 
  AND token = 'LFsX6wv+qcMR0M2ByaA26WdXkKfST8kVAVcqZQzy8K4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}