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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c090f761d7725f3499291dc4a0096f76ee6518d24b5ac91b0be2b9553d1ef385' 
  AND token = 'pPKCAtWiyJUI2fGuOoUNDDYezxA4TXDhq9Y2cNb5EyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}