SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5b589d663a146a0824901664b8a9bb7dd2308b92b43387a8dcd7fd495def8bd' 
  AND token = 'p19ZrBOSXfmO10c5WJsvECBoSmsbESeB+XHyd0ij6SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}