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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb3e20bb2353fa7f7cb043358d41fa6fb0e336fb18718098c6f62b2abc66744b' 
  AND token = '01tdBATZAifOl8e2mKvRthh1+HFzHFJthfDVqF05plI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}