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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdd7049048026a4c9fa8dbfa16a24476f4fe94e54887e0c697ca3784081f9714' 
  AND token = 's+7EjwiMOuz7HgwWC/OBrgttaFRK8tcd3hdQf4PP5/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}