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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e072ca67500ba1147435c7734e68055053fdd35c55439ad7e7aa5784688a303' 
  AND token = 'lcqyZo+Xgv3eJ0cwAa8aRYJFDFXqhXJ+doF8o+wY/Hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}