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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65365e78abd185d1c9444b6f88398182947e3835f86fb8cd005c2ba01f0a02f0' 
  AND token = 'Z5WZKl6gbyA22Akb3AMAf1OwG4DiRmb7kmIFsHRdigU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}