SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c5affbc7765c4816d30cf7a7cc4d5df422c2ae460afc0374a7f4f4e74d8a240' 
  AND token = 'awW+kOXgC/j142wBTTSoRJ2St2AGbpUE6wm2uYIV7Ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}