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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3db80842b3a6f0eb295487bf282a7e36313756c4d447017a4335490d49b34e3e' 
  AND token = 'QMzv75gcOo8sq7sZUyu3fmORLUHgOamO0MVJimO14Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}