SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08d63feb7df011e1ed4404dd56cc3323792d5da0d75a4c21eb1b338651f6b016' 
  AND token = 'JboV2UuXY0MK0DVrn+nytqLk0ZWI4Ssph2RLM0ghmc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}