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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22bdfa0e8cb5306fee4b858cb438d04e9855fd0e182ed2349da4ddb845aef94' 
  AND token = 'nh6TyMKfFvMHf8G8Lxwh75HE20Qmw5rCT9nSvhFlF8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}