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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15aa4beb6d81f98d8cabdb7e6752cffe363c19497d76428d48aeb59a5ba6e506' 
  AND token = '2/ndP9VW6H+un0/SRtBhWSnYIxEJKQxOOujKMtEpyH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}