SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '600f64d09bd5e2dec6ef2eef2efe93e8b6443ecc9dbe8fd139b5875c54878101' 
  AND token = 'WexxKV4/HQFUaqMzXrO4z+bbNrgIiJWlm0U2fncKII0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}