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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3709963eef75afc3c7d25a9ca1bb15f3c206955c0fb168472f3e894a9beda61b' 
  AND token = 'ESqQDgbam6GTrn2M2IOKMYTkld0r1svV0M+SEKKMEak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}