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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380605e9c94e79068ddd9fcaaa311e912295b50ac2d2d1bebd75317c448192b8' 
  AND token = '8EuNFAAYh3A9RE//NTgDZw64gsxoSuMct3yc2ZW4Hvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}