SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f033126f8486f5c3193437c88428531b70445e8a3adf647fc48110e3887c32e1' 
  AND token = 'Is5KR0CUd3zkc7rzYFFCSPcdz+uXBmXM5bDzhKJ1AS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}