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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df53846d000bf132df21a354d13bb057f8b1503f4f23e10943a1fbe41c0cacf' 
  AND token = '+rBWV9PPeBPsUIGbz6shdptajnoa1GYipaP1fespHNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}