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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aecd3ba08056c0944e2939113db427ec9a08f01e89e43a7f6bdf7e996fed7589' 
  AND token = 'VxoifDAHMJ2gKsG4uHbaalb1V9Sudqrx0mQIhPlvF4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}