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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd885b8f48e288357fe4e6fa1163976bf49b1d45819320b8d405e77cd627be4dd' 
  AND token = 'Qi/Yv1kpNRgpFwXvJ4awmJG2tb0Nxgc+Isb4FpfaFs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}