SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c2187c599432f272d1133d0f6fe7922208ecaefd87b203fd69a78cb6f77664' 
  AND token = 'SOJp3nV9+cn/LiKZuHMfzBmAfKa7L6nNXZhPusSn5ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}