SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b61aed052f54011bb6622000430967dc9c8f3e1d16c04add1bacf270c90eef' 
  AND token = 'dlRuebbeTk8uebUpmHvPdos418eA2l77+fUIIyT4ido=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}