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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe0148d37ef3c9b03d48f00fb9ea06955424775f1ba269ee3223d878a4cc87bc' 
  AND token = 'JDiRGb7gonAgDAm7lzCBhrzO8V21E4mr5gsX49eIAhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}