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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '078dfc1c5c1adc01659d6d5c569b1127af09ff3faa642a7dafca0a7c7c2adb52' 
  AND token = 'O4qCz1/mYBqzxv5jnXFQHCtROqH1szMJo4p2sotDThA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}