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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb016ef01e02760e647419559135d95745616005d6b92c7908e55da790d252bf' 
  AND token = 'FXFEtFoMeCE6Vgyfy+8m4H6sg6/8w97BYJdefWljylI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}