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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '278c94529cabf761ca84a7cc1563356059220d51625c1aee24669dad9ff455ba' 
  AND token = 'fH2Wu0xsXZ35KrIyvRQh2ur1TBJMSIQfWZdSA+lX4O8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}