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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c10655c2b534e8875ea67d9be20d34972d32553dbc5c9b338107ea5d8b46bd32' 
  AND token = '3jbqiDGYzjPj2CB0ok5dLVahktWUN6W/Zsn0uSvv7Hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}