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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '844ef93698d2359165b4f782e0f68ac4307b74817257d12f4f3f25bbc4ddd8c0' 
  AND token = 'IRWRmdAGwTbRDkPtv8dc9aJlqyCNPTuZoZWN+vzalZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}