SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfacc3d168fe4f270b1f9b9c9f784f31a11b1983db300dd03a3818b838bfb3fa' 
  AND token = 'XK2zEwYF5tcFNzpBi/7iaRRHVFijw7gKJHVnxCt+PoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}