SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc6ad394e86911ea603bad9ad6462a0f1649a27af5186986e7431b636d2d264f' 
  AND token = 'zx41yYqM43i6l1juKQszqFUE9XAK29qDNjw/6zxj1y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}