SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59212c993f00b0ac7901d91bf4ffeacd87ee37b5188329e8780eeff8867021f9' 
  AND token = 'uEKUxoxTKESzcAFfDr18XZ+wJIsWl1PsZWrr01Dw+58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}