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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f63b5937b394f96cc2f2e9ec0967e2a37236877f358ce2ef286d0939d0d5f3a8' 
  AND token = 'dS/X22L5W9omDp5/TCN7o1ntUfCYSXmTo5zFHiDcVK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}