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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa343717f0d606dd3d439cd97026ac755b896e6f0d80ea75e7ec4e61fb2f2098' 
  AND token = 'FXUuoe/JQmBaLA7mWsBpneeUXWJ3OYwhYHULleK8XXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}