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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c25a8887997d28910cf7cb035e9e2b4800ae7a4b105a91ef19437cae3df06ed2' 
  AND token = '7b0hSB1GMs9zu5gLDLWmGfqYG0oiDOX9kBgJrJfZ4ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}