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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d073b1059bbc4d4befc0ddd4676d04f2c767b3c2df34f11c9b14fe2924b19a1' 
  AND token = 'OLrNVqOVxEHpjfWL40Hz/tf2qk4uHxJQC0fJ+GdNx9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}