SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbc468ad5f4c492cff8c57fbb65ed06fee0c388c8cea303d6957a88c94a4a923' 
  AND token = 'Vp0M/Y+skT9LfOCSsYj4CuvBq6lBPq+p3WZSR+nntrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}