SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55d7a122147b53495c6e120e4eaf40dc728f64def42e8f420ace510b129cadc9' 
  AND token = 'CjWAvicaD8GstMFrDI1CEgPZqA+sEFmCh+wXFgDRnok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}