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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c77f46d2b467b347e8ad766a403d1a1fada6a96772c574bfb8227542eabd597' 
  AND token = 'rv0UI/iTNyYIqW95NOH4SZb6xO6mAzQQZxYWBAntdSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}