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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea87ade50c27e66b396e8abca537308b3fc38c0e92b407b92521782ffea4168f' 
  AND token = 'vWw43TZ0YmCoqSo4iB08KjkfhUOI9IWkR3bdc/IDOfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}