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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '216232e6491e45174a0c62e621eae31d846b7ec0a4aff4bb5ccbabae26aae776' 
  AND token = '/8zj1/plE+8Dddgp2EaRYouziWLYkTnnwIo5V+WMpbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}