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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c53388bafde9f7e16becffa8fdcd663b9fc3a14f7c3ac8ad1f60b532aabe600' 
  AND token = '5IZBtXfzaI62Xc/6o2+99C1STCRZb07D02QTH8wiYJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}