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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '124d1f96fcf0c905332ec7e1745564417648fe78b74b537c41bb0b496ef9dd99' 
  AND token = 'siAnQ6yz1DjNVwN87ZxQVycdnJ5NQPIuuNz4EhQsdC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}