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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de877e65c8c042fb3ad0681cd6e183313ddcd03fe9ab1858a759bbde550771b1' 
  AND token = 'CaLIG6xnKwcPj3faldZSmmJuq8/5hnd3eQ/cAWpM+rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}