SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '807081b7e94b4d12b894027275f5c07fd7ff9a8480511ba94d264071747495c6' 
  AND token = 'y12akVk+R4VNXxmV3/KsDJbrJ2T0jUpTmabmVsdiyMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}