SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '827506f3c1b5f321257c703521f5afbe698d55f8481a0c6f89dc65494474724b' 
  AND token = '3g1OUOJF0k/a21pk+f4H3aLi7imVR5/+AUtrDPiNlUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}