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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4e2fa1810a19133039dd8d3823dc3b78f4492b711935f5ed9b80751beff65f9' 
  AND token = 'y+aC+wsqlsjo6wOy2xw/Q2hpBHTD9S3RFTTeRoEO1ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}